Loading...
 
Toggle Health Problems and D

1.7 X less risk of Heart Failure death if previously had taken any amount of vitamin D - Jan 2022

Association between Vitamin D and Heart Failure Mortality in 10,974 Hospitalized Individuals

Nutrients 2021, 13(2), 335; https://doi.org/10.3390/nu13020335
by Kenya Kusunose 1,*ORCID,Yuichiro Okushi 1,Yoshihiro Okayama 2,Robert Zheng 1,Miho Abe 1,Michikazu Nakai 3,Yoko Sumita 3,Takayuki Ise 1,Takeshi Tobiume 1,Koji Yamaguchi 1,Shusuke Yagi 1,Daiju Fukuda 1,Hirotsugu Yamada 4,Takeshi Soeki 1,Tetsuzo Wakatsuki 1 andMasataka Sata 1

Image
A broad range of chronic conditions, including heart failure (HF), have been associated with vitamin D deficiency. Existing clinical trials involving vitamin D supplementation in chronic HF patients have been inconclusive. We sought to evaluate the outcomes of patients with vitamin D supplementation, compared with a matched cohort using real-world big data of HF hospitalization. This study was based on the Diagnosis Procedure Combination database in the Japanese Registry of All Cardiac and Vascular Datasets (JROAD-DPC). After exclusion criteria, we identified 93,692 patients who were first hospitalized with HF between April 2012 and March 2017 (mean age was 79 ± 12 years, and 52.2% were male). Propensity score (PS) was estimated with logistic regression model, with vitamin D supplementation as the dependent variable and clinically relevant covariates.
On PS-matched analysis with 10,974 patients, patients with vitamin D supplementation had

  • lower total in-hospital mortality (6.5 vs. 9.4%, odds ratio: 0.67, p < 0.001) and
  • in-hospital mortality within 7 days (0.9 vs. 2.5%, OR, 0.34, and
  • in-hospital mortality within 30 days 3.8 vs. 6.5%, OR: 0.56, both p < 0.001)

In the sub-group analysis mortalities in patients with age < 75, diabetes, dyslipidemia, atrial arrhythmia, cancer, renin-angiotensin system blocker, and ß-blocker were not affected by vitamin D supplementation. Patients with vitamin D supplementation had a lower in-hospital mortality for HF than patients without vitamin D supplementation in the propensity matched cohort. The identification of specific clinical characteristics in patients benefitting from vitamin D may be useful for determining targets of future randomized control trials.

 Download the PDF from Vitamin D Life

Suspect that something other than Vitamin D might have created the benefit

Example: Vitamin D may have been just one of many things that the person was doing to improve their health

Pages with HEART FAILURE in title (43 as of April 2022)

This list is automatcially updated

Items found: 45
Title Modified
Risk of heart failure increased 1.4X if low vitamin D – meta-analysis Dec 2022 28 Dec, 2022
1.7 X less risk of Heart Failure death if previously had taken any amount of vitamin D - Jan 2022 14 Apr, 2022
Chronic Heart Failure reduced by 4,000 IU daily for a year – RCT April 2016 07 Oct, 2021
COVID-19 hospitalizations: 63% associated with diabetes, obesity, hypertension or heart failure – Feb 2021 15 Apr, 2021
Patients on Hemodialysis 3X more likely if die of heart failure if low Magnesium – meta-analysis Jan 2021 26 Mar, 2021
After Heart Failure Blacks are 45 percent more likely to re-enter the hospital in a month – Oct 2020 10 Oct, 2020
Heart Failure may be associated with low Zinc (drugs and gut restrict Zinc) - Jan 2020 15 Jan, 2020
Senior veterans with Heart Failure were 1.8X more likely to be hospitalized if low vitamin D – Feb 2020 31 Dec, 2019
Heart Failure and Vitamin D meta-analyses - 2016, 2019 24 Aug, 2019
Few people have enough EPA (an Omega-3) to reduce heart failures – July 2019 16 Jul, 2019
Heart Failure 15X more likely if poor VDR, even if good level of vitamin D (China) – March 2019 23 Mar, 2019
Small or infrequent doses of vitamin D do not reduce heart failure much – meta-analysis Jan 2018 24 Nov, 2018
Heart Failure is predicted by PTH (but vitamin D both prevents and treats HF) – Jan 2018 31 Mar, 2018
Heart Failure Quality of Life greatly improved by 10,000 IU of vitamin D – RCT Oct 2017 01 Nov, 2017
Heart Failure patients 4 X less likely to benefit from pacemaker (CRT) if low vitamin D – Oct 2017 11 Oct, 2017
Anemia (in heart failure) not treated by Vitamin D (they should have added Iron) – RCT Aug 2017 25 Aug, 2017
Heart Failure with depression increases risk of death by 9.5 X if low vitamin D – Aug 2017 23 Aug, 2017
Acute Heart Failure length of stay and readmission rates cut in half if high vitamin D – Aug 2017 20 Aug, 2017
Heart failure among 137 seniors 12X more likely if low vitamin D – Aug 2017 17 Aug, 2017
Chronic Heart Failure – not enough evidence that Vitamin D helps (but lots of evidence for other cardiovascular problems) – Aug 2017 14 Aug, 2017
Heart Failure not helped by Vitamin D (several strange things about the trial) – RCT May 2017 24 May, 2017
Congestive Heart Failure patients helped with Vitamin D intervention – May 2013 07 Apr, 2017
Vitamin D augmented conventional Congestive Heart Failure treatment in perhaps 10 ways – case reports April 2017 07 Apr, 2017
Chance of death after heart failure reduced by 1000 IU of vitamin D – Feb 2012 04 Jan, 2017
Chronic Heart Failure not treated by Vitamin D, if dose size is ignored – meta-analysis Oct 2015 20 Oct, 2015
Congestive heart failure in infants virtually cured by 1000 IU of vitamin D – RCT Feb 2012 20 Oct, 2015
Heart failure markers reduced by 400 IU of vitamin D and Calcium (surprise) – RCT Jan 2015 18 Mar, 2015
More blood was pumped by those getting 800,000 IU of vitamin D after heart failure – RCT Oct 2013 16 Mar, 2015
Heart Failure early death 2X more likely if less than 20 nanograms of vitamin D – June 2012 11 Feb, 2015
Seniors with Heart Failure helped by daily 4,000 IU of vitamin D (increase 16 ng) – RCT Aug 2014 25 Jul, 2014
Heart pumped more blood after heart failure if more vitamin D – Nov 2010 27 Oct, 2013
Chronic Heart Failure helped with 2,000 IU of vitamin D (PRA reduced) – RCT June 2013 30 Jun, 2013
Heart failure 2X more likely if less than 20 ng of vitamin D – Sept 2012 13 Apr, 2013
Death in less than 2 years of Heart Failure associated with low vitamin D - April 2012 08 Aug, 2012
96 percent of heart failure patients had less than 30 ng of vitamin D – March 2011 28 Apr, 2012
Patent for patients of Chronic Heart Failure includes vitamin D – June 2011 16 Jun, 2011
Heart Failure associated with vitamin D deficiency – Feb 2011 01 Apr, 2011
Review is unsure if supplementing vitamin D will decrease heart failure – Feb 2011 13 Feb, 2011
Calcium with Vitamin D2 then D3 helps A-A after heart failure – Jan 2011 18 Jan, 2011
Review of heart failure and vitamin D mechanisms – Jan 2011 13 Dec, 2010
Heart Failure 3X more likely if less than 30 ng of vitamin D – Sept 2010 16 Sep, 2010
Review of vitamin D and heart failure – Aug 2010 02 Sep, 2010
Lack of vitamin D is a predictor of heart failure – Sept 2010 02 Sep, 2010
The prognostic value of vitamin D in heart failure – July 2010 28 Jul, 2010
Can vitamin D improve quality of life for seniors with heart failure -2010 02 Jun, 2010

Vitamin D Life Meta-anlysis pages with HEART FAILURE in title

This list is automatically updated

Items found: 4

Vitamin D Life - Cardiovascular category

507 items In Cardiovascular category

Cardiovascular category is associated with other categories: Diabetes 31, Omega-3 31 , Vitamin K 25 , Intervention 22 . Mortality 20 , Skin - Dark 18 , Magnesium 17 , Calcium 14 , Hypertension 14 , Trauma and surgery 13 , Stroke 13 , Kidney 12 , Metabolic Syndrome 11 , Seniors 10 , Pregnancy 8 as of Aug 2022

Created by admin. Last Modification: Thursday April 14, 2022 18:45:50 GMT-0000 by admin. (Version 8)
1.7 X less risk of Heart Failure death if previously had taken any amount of vitamin D - Jan 2022        
2101 visitors, last modified 14 Apr, 2022,
Printer Friendly Follow this page for updates
Cardiovascular 461 Mortality and D 287
Page actions
Print
Edit Files 2

Attached files

ID Name Comment Uploaded Size Downloads
17414 HF survival.jpg admin 14 Apr, 2022 26.32 Kb 203
17413 Heart Failure Mortality.pdf admin 14 Apr, 2022 945.72 Kb 162